|
KMID : 0914820110110020122
|
|
Journal of the Korean Gastric Cancer Association
2011 Volume.11 No. 2 p.122 ~ p.125
|
|
|
Mixed Exocrine and Endocrine Carcinoma in the Stomach: A Case Report
|
|
Lee Han-Hong
Jung Chan-Kwon
Jung Eun-Sun
Song Kyo-Young
Jeon Hae-Myung
Park Cho-Hyun
|
|
|
Abstract
|
|
|
|
We report a rare case of the coexistence of a gastric small cell neuroendocrine carcinoma with a gastric adenocarcinoma. A 62-year-old man presented with epigastric soreness for 1 month. Esophagogastroduodenoscopy revealed a Borrmann type I tumor at the lesser curvature of the lower body of the stomach. The patient underwent a distal gastrectomy with D2 lymph node dissection and the resected specimen exhibited a 3.5x3.5 cm sized, fungating lesion. Two separated, not intermingling, lesions with non-adenocarcinoma components encircled by well differentiated adenocarcinoma components were identified microscopically. The non-adenocarcinoma component showed neuroendocrine features, such as a solid and trabecular pattern, and the tumor cells showed a high nuclear grade with minimal cytoplasm, indistinct nucleoli, and positive response for synaptophysin, CD56. The final pathological diagnosis was a gastric mixed exocrine-endocrine carcinoma (MEEC) composed of an adenocarcinoma and small cell neuroendocrine carcinoma of the collision type.
|
|
|
KEYWORD
|
|
|
Stomach neoplasms, Neuroendocrine tumor, Adenocarcinoma
|
|
|
FullTexts / Linksout information
|
|
 
|
|
|
Listed journal information
|
|
  
|